Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
USERS' SCORE
Good
Based on 5 Reviews
8.2
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend 
134 mg (1 Billion CFU§)
Lactobacillus rhamnosus (GR-1®) 
 
 
Lactobacillus reuteri (RC-14®) 
 
 

Top Medical Research Studies

9
Lacticaseibacillus rhamnosus shows promise
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.

Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
Read More
9
Bacteriocin LSB1 shows promise
We investigated the effectiveness of a new bacteriocin, LSB1, derived from Lactobacillus plantarum, in combating Staphylococcus argenteus—a harmful bacteria linked to food poisoning. This bacteriocin showed strong antibacterial properties, significantly inhibiting both the growth of planktonic and biofilm forms of the bacteria. LSB1 demonstrated notable stability under various conditions and a relatively low minimum inhibitory concentration. While the study indicates promising potential for LSB1 as a natural food preservative, more research is needed to fully understand its applications in food safety.
Read More
8
Lactobacillus reduces harmful E. coli
We examined how Lactobacillus can help reduce harmful E. coli in the rumen, the large fermentation chamber in cows. By using live Lactobacillus casei and its metabolites in a controlled lab setting, we discovered that one specific treatment, Lactobacillus casei with peanut flour, decreased E. coli by 2.68 logs after 72 hours. This study indicates that the metabolites from Lactobacillus can positively influence the rumen environment, which could be helpful in managing foodborne pathogens from cattle.
Read More

Most Useful Reviews

9
Quick cystitis relief
8 people found this helpful
This product helped with cystitis from the very first capsule! I recommend taking it alongside apple fibre from Now Foods. I was greatly helped by this combination, and I have found it effective.
Read More
7.5
Promotes bacterial balance
8 people found this helpful
I like this product very much! I recently experienced vaginitis, and upon researching, I found that this product can effectively maintain the good bacteria in the vagina, so my first purchase from iHerb was to buy it! After taking it for a month, if I notice excessive secretions or before my menstrual period, I will take two capsules. Usually, I take one capsule a day. I hope that consistent use will stabilise my condition. It's a reasonably priced health food that can support the body, and I will definitely continue to buy it in the future!
Read More
6
Effective for imbalance
1 people found this helpful
I like the quality of Jarrow supplements, including these probiotics. I’m currently taking them to normalise the female microflora, and I believe the supplement is working: itching and irritation have decreased (though I didn’t have thrush, just some imbalance). The capsules are very small, and the dosage is one piece per day with or without food, but it is advised not to wash it down with anything hot. The package contains 60 capsules, making it last for many weeks of use. The jar is protected by a foil membrane.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 9 Researches
8.1
  • All Researches
9
Probiotic effects against E. coli
We explored how Lactobacillus K5 could help mice fend off E. coli O157:H7 infections. In our study, we observed that treating the mice with K5 ahead of exposure reduced their symptoms and helped maintain a healthier gut environment.

The benefits included less inflammation and more diversity in gut bacteria compared to untreated mice. Additionally, K5 boosted beneficial substances that protect the gut. Overall, this study shows promise for K5 in developing probiotic treatments for foodborne illnesses.
Read More
9
Bacteriocin LSB1 shows promise
We investigated the effectiveness of a new bacteriocin, LSB1, derived from Lactobacillus plantarum, in combating Staphylococcus argenteus—a harmful bacteria linked to food poisoning. This bacteriocin showed strong antibacterial properties, significantly inhibiting both the growth of planktonic and biofilm forms of the bacteria. LSB1 demonstrated notable stability under various conditions and a relatively low minimum inhibitory concentration. While the study indicates promising potential for LSB1 as a natural food preservative, more research is needed to fully understand its applications in food safety.
Read More
9
Lacticaseibacillus rhamnosus shows promise
We explored the potential of Lacticaseibacillus rhamnosus GG as a probiotic treatment against avian pathogenic E. coli (APEC) in chickens. Our study showed that this probiotic significantly reduced APEC colonization in the chickens' cecum and improved the balance of gut microbiota over a 24-hour period.

Through laboratory evaluations, we detected novel bioactive peptides in the probiotic's culture supernatants, which may contribute to its antibacterial properties. While the results are promising for poultry health, more research is needed to optimize its use in real farming conditions.
Read More
8
Lactobacillus reduces Campylobacter levels
In our examination, we assessed how Lactobacillus-fermented rapeseed meal (LFRM) influences the presence of Campylobacter jejuni in broilers exposed to contaminated litter.

The findings revealed that LFRM not only boosted growth performance but also significantly lowered the concentration of C. jejuni in the ceca.

This reduction appears linked to a decrease in critical gene pathways necessary for the bacteria's survival and virulence. Overall, LFRM shows promise as a helpful approach in curbing foodborne pathogens in poultry.
Read More
8
Lactobacillus reduces H. pylori impact
We explored how live and pasteurized Lactobacillus crispatus strain RIGLD-1 could help fight against Helicobacter pylori, known to cause stomach inflammation and increase cancer risk. By using a variety of tests on gastric cells, we found that both forms of Lactobacillus significantly reduced the bacterium's ability to cling and invade these cells.

Additionally, they helped lower markers of inflammation in the cells, promoting a more balanced immune response. Overall, both live and pasteurized Lactobacillus crispatus showed promise as potential probiotics to combat H. pylori-related issues.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Quick cystitis relief
8 people found this helpful
This product helped with cystitis from the very first capsule! I recommend taking it alongside apple fibre from Now Foods. I was greatly helped by this combination, and I have found it effective.
Read More
7.5
Promotes bacterial balance
8 people found this helpful
I like this product very much! I recently experienced vaginitis, and upon researching, I found that this product can effectively maintain the good bacteria in the vagina, so my first purchase from iHerb was to buy it! After taking it for a month, if I notice excessive secretions or before my menstrual period, I will take two capsules. Usually, I take one capsule a day. I hope that consistent use will stabilise my condition. It's a reasonably priced health food that can support the body, and I will definitely continue to buy it in the future!
Read More
6
Effective for imbalance
1 people found this helpful
I like the quality of Jarrow supplements, including these probiotics. I’m currently taking them to normalise the female microflora, and I believe the supplement is working: itching and irritation have decreased (though I didn’t have thrush, just some imbalance). The capsules are very small, and the dosage is one piece per day with or without food, but it is advised not to wash it down with anything hot. The package contains 60 capsules, making it last for many weeks of use. The jar is protected by a foil membrane.
Read More
7.5
Rapid vaginitis improvement
2 people found this helpful
Vaginitis troubled me for a year, but it has improved within a few days of taking this supplement, and I have not encountered any issues with constipation. It's a beneficial health product for women.
Read More
7.5
Improves gut discomfort
1 people found this helpful
I take this probiotic along with NOW Foods' Candida Support and feel a noticeable improvement in my intestinal condition; bloating and discomfort occur much less frequently. While my candida condition has improved, it’s not yet at 100% as I would like. I believe ongoing use for a couple of months will help me gauge the full effect. I haven’t had it sown for a long time, but occasionally, sensations occur that I can’t mistake for anything else; it's definitely her.
Read More

Frequently Asked Questions

9
Quick cystitis relief
8 people found this helpful
This product helped with cystitis from the very first capsule! I recommend taking it alongside apple fibre from Now Foods. I was greatly helped by this combination, and I have found it effective.
7.5
Promotes bacterial balance
8 people found this helpful
I like this product very much! I recently experienced vaginitis, and upon researching, I found that this product can effectively maintain the good bacteria in the vagina, so my first purchase from iHerb was to buy it! After taking it for a month, if I notice excessive secretions or before my menstrual period, I will take two capsules. Usually, I take one capsule a day. I hope that consistent use will stabilise my condition. It's a reasonably priced health food that can support the body, and I will definitely continue to buy it in the future!
6
Effective for imbalance
1 people found this helpful
I like the quality of Jarrow supplements, including these probiotics. I’m currently taking them to normalise the female microflora, and I believe the supplement is working: itching and irritation have decreased (though I didn’t have thrush, just some imbalance). The capsules are very small, and the dosage is one piece per day with or without food, but it is advised not to wash it down with anything hot. The package contains 60 capsules, making it last for many weeks of use. The jar is protected by a foil membrane.
7.5
Improves gut discomfort
1 people found this helpful
I take this probiotic along with NOW Foods' Candida Support and feel a noticeable improvement in my intestinal condition; bloating and discomfort occur much less frequently. While my candida condition has improved, it’s not yet at 100% as I would like. I believe ongoing use for a couple of months will help me gauge the full effect. I haven’t had it sown for a long time, but occasionally, sensations occur that I can’t mistake for anything else; it's definitely her.
7.5
Rapid vaginitis improvement
2 people found this helpful
Vaginitis troubled me for a year, but it has improved within a few days of taking this supplement, and I have not encountered any issues with constipation. It's a beneficial health product for women.
9
Probiotic effects against E. coli
We explored how Lactobacillus K5 could help mice fend off E. coli O157:H7 infections. In our study, we observed that treating the mice with K5 ahead of exposure reduced their symptoms and helped maintain a healthier gut environment.

The benefits included less inflammation and more diversity in gut bacteria compared to untreated mice. Additionally, K5 boosted beneficial substances that protect the gut. Overall, this study shows promise for K5 in developing probiotic treatments for foodborne illnesses.
8
Lactobacillus pentosus shows selective inhibition
We observed the potential of Lactobacillus pentosus to combat foodborne bacteria like Bacillus cereus and Klebsiella pneumoniae in our study. Using cell-free supernatants, we tested its antimicrobial effects through agar well diffusion methods.

While we noted a clear zone of inhibition against B. cereus, K. pneumoniae showed resistance and did not respond to treatment. The heat and pH stability of the bacteriocin from L. pentosus suggests it could be useful in the food industry for preventing food poisoning from B. cereus. However, it's not effective against K. pneumoniae.
7
LGR-1 shows potential against B. cereus
In our study, we examined how Lactobacillus rhamnosus GR-1 (LGR-1) could protect bovine mammary epithelial cells from the harmful effects of Bacillus cereus, a common foodborne pathogen. By pretreating cells with LGR-1, we found that it helped maintain tight junction integrity and lowered inflammatory responses triggered by B. cereus. This suggests that LGR-1 might serve as a probiotic alternative to antibiotics and could prevent mastitis in dairy cows, promoting better food safety overall. However, the results do not indicate any significant direct benefits for human food poisoning cases.
7
Probiotics enhance fish health outcomes
This research investigates how probiotics, specifically Lactobacillus strains, can impact food-borne infections. Using a zebrafish model, we treated the fish with Lactobacillus delbrueckii, Lactobacillus acidophilus, or both, and compared them to a control group.

The results revealed that fish in the combination treatment group showed significant improvements in immune responses and intestinal health over time. Notably, they had higher villus lengths and an increased number of goblet cells. However, the control group, which was solely infected, did not fare as well.

Overall, probiotics demonstrate promise for enhancing food safety and public health in aquaculture.

References

  1. Liu D, Li C, Cao T, Lv X, Yue Y, et al. K5 Prevents Enterohaemorrhagic O157:H7 Infection in Mice through the Modulation of the Gut Microbiota. Nutrients. 2024;16. doi:10.3390/nu16081164
  2. Khattak F, Galgano S, Pedersen NR, Hui Y, Matthiesen R, et al. Supplementation of lactobacillus-fermented rapeseed meal in broiler diet reduces Campylobacter jejuni cecal colonization and limits the l-tryptophan and l-histidine biosynthesis pathways. J Sci Food Agric. 2024;104:5474. doi:10.1002/jsfa.13378
  3. Fakharian F, Sadeghi A, Pouresmaeili F, Soleimani N, Yadegar A. Immunomodulatory effects of live and pasteurized Lactobacillus crispatus strain RIGLD-1 on Helicobacter pylori-triggered inflammation in gastric epithelial cells in vitro. Mol Biol Rep. 2023;50:6795. doi:10.1007/s11033-023-08596-x
  4. Akhtar S, Nawaz SK. Antimicrobial activity of Lactobacillus pentosus against the Bacillus cereus and Klebsiella pneumoniae strains. New Microbiol. 2023;46:207.
  5. Aditya A, Rahaman SO, Biswas D. Impact of Lactobacillus-originated metabolites on enterohemorrhagic E. coli in rumen fluid. FEMS Microbiol Ecol. 2022;98. doi:10.1093/femsec/fiac128
  6. Shan Q, Liu N, Wang X, Zhu Y, Yin J, et al. Lactobacillus rhamnosus GR-1 attenuates foodborne Bacillus cereus-induced NLRP3 inflammasome activity in bovine mammary epithelial cells by protecting intercellular tight junctions. J Anim Sci Biotechnol. 2022;13:101. doi:10.1186/s40104-022-00752-w
  7. Ehsannia S, Ahari H, Kakoolaki S, Anvar SA, Yousefi S. Effects of probiotics on Zebrafish model infected with Aeromonas hydrophila: spatial distribution, antimicrobial, and histopathological investigation. BMC Microbiol. 2022;22:167. doi:10.1186/s12866-022-02491-4
  8. Zhang YM, Jiang YH, Li HW, Li XZ, Zhang QL. Purification and characterization of Lactobacillus plantarum-derived bacteriocin with activity against Staphylococcus argenteus planktonic cells and biofilm. J Food Sci. 2022;87:2718. doi:10.1111/1750-3841.16148
  9. Kathayat D, Closs G, Helmy YA, Deblais L, Srivastava V, et al. In Vitro and In Vivo Evaluation of Lacticaseibacillus rhamnosus GG and Bifidobacterium lactis Bb12 Against Avian Pathogenic Escherichia coli and Identification of Novel Probiotic-Derived Bioactive Peptides. Probiotics Antimicrob Proteins. 2022;14:1012. doi:10.1007/s12602-021-09840-1
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